What is MXE?

Methoxetamine is a research chemical with dissociative and psychedelic properties similar to ketamine and phencyclidine (PCP). It was originally developed by an underground chemist in the UK as an allegedly safer alternative to ketamine. Since ketamine is an established, rapid-acting antidepressant, MXE is believed to possess similar antidepressant and analgesic properties. On these fronts, MXE may have therapeutic potential for major depression and a variety of pain syndromes such as phantom limb syndrome.

Street Names of MXE

MXE, Mexxy, M-ket, Kmax, Special M, MA, Legal ketamine, Minx, Jipper, Roflcoptr

Chemistry of MXE

Methoxetamine, also known as 3-MeO-2′-oxo-PCE, is an eticyclidine (PCE) derivative and structural analog of ketamine. Methoxetamine is a contraction of “methoxy-ketamine”. The name refers to a methoxy group that replaced a chloro group in the chemical structure of ketamine.

Like ketamine and PCP, MXE belongs to a family of compounds known as the arylcyclohexylamines. The name refers to their molecular structure, which is composed of an aryl group bound to a cyclohexylamine unit. They are a broad group of pharmaceutical and designer drugs known for their dissociative, anesthetic, and psychedelic properties due to their shared mechanism of action as NMDA antagonists.

Like ketamine, MXE contains two stereoisomers. Stereoisomers are compounds with the same molecular formula but differ in the spatial arrangement of their atoms. MXE is found on the gray market largely as the racemic mixture, though enantiopure batches (batches of only 1 of the 2 stereoisomers) have been distributed.

Ways to Consume MXE

Methoxetamine is typically found in powder form as a white or off-white hydrochloride salt. It is administered in a multitude of forms, including:

Oral (capsules or dissolved in solution)
Sublingual
Nasal insufflation
Intramuscular injection
Intravenous injection
Rectal

Each route produces a different onset of action, duration, and intensity of effects.

updated at June 2023 - Tags: order Methoxetamine, Methoxetamine